L’acide valproïque, antiépileptique largement prescrit, peut être à l’origine d’ intoxications graves. Après avoir décrit un cas d’intoxication sévère avec. Publisher: Selon des sources tertiaires, la prise concomitante de lorazépam et d’ acide valproïque causerait une interaction médicamenteuse. Ici, nous rapportons un cas rare de SJS déclenché par une combinaison de clobazam, la lamotrigine et l’acide valproïque chez un garçon de 7.
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Simple Structure Advanced History. The owners of this website hereby guarantee to respect the legal confidentiality conditions, applicable in France, and not to disclose this data to third parties. Desmaretz bN. Previous Article Intoxication par le chloralose: Our case suggests that a drug-drug interaction between valproate, lamotrigine and clobazam contributed to the development of SJS.
Acidose lactique sur intoxication volontaire à l’acide valproïque – EM|consulte
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You may thus request that your data, should it be inaccurate, incomplete, unclear, outdated, not be used or stored, be corrected, clarified, updated or deleted. Alluin bJ.
Access to the full text of this article requires a subscription. Access to the text HTML. Depakin chrono [Trade name]. Personal information regarding our website’s visitors, including their identity, is confidential. Contact Help Who are we? Myproic acid [Trade name].
Outline Masquer le plan. If you want to subscribe to this journal, see our rates You can purchase this item in Pay Per View: Structure incompatible with current estimation method! Access to the full text of this article requires a subscription.
Antiepileptic drugs AEDs are used in combination, leading to potential pharmacokinetic or pharmacodynamic interactions, causing more adverse effects than might occur when the AED is taken as monotherapy. Boyer cJ. However, this recommendation could not be validated through an analysis of patients exposed to this interaction in the clinical setting or through a review of the literature.
Journal page Archives Contents list. When the clobazam was added to valproic acid and lamotrigine co-medication, the lamotrigine dose should have been decreased.
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Click to predict properties on the Chemicalize site. Stevens-Johnson Syndrome SJS and toxic epidermal necrolysis TEN are diseases within the spectrum of severe cutaneous adverse reactions affecting skin and mucous membranes. Access to the PDF text. Because of inadequate seizure control, lorazepam was replaced with clobazam.
Epival er [Trade name].
WO1981000562A1 – Sel melange d’acide valproique – Google Patents
To identify site-specific practices and assess clinical responses to the interaction between valproic acid and lorazepam. Access to the text HTML. Epilepsy, 10,valprpique Four weeks after the addition of clobazam, the patient developed SJS with a generalized rash, fever, with liver and kidney involvement, and eosinophilia one week after the initiation of treatment.
Valporique may thus request that your data, should it be inaccurate, incomplete, unclear, outdated, not be used or stored, be corrected, clarified, updated or deleted. Gauthier aA. Publication or Magazine Article. Depakote ER [Trade name]. Rate constants can NOT be estimated for this structure! Compounds with the same molecular formula Compounds with the same skeleton Use this molecule in a structure search.
Semi-standard non-polar; Column diameter: