CANCER DE AMPULA DE VATER PDF

CANCER DE AMPULA DE VATER PDF

Carcinomas of the Ampulla of Vater are rare tumors, accounting for % of A review of chemotherapy options available for ampullary cancer. Metastasis of breast cancer to major duodenal papilla Palabras clave: Ampolla de Vater; Neoplasias de la mama; Ictericia (fuente: DeCS BIREME). Periampullary tumors are neoplasms that arise in the vicinity of the ampulla of Vater. Neoplasms that arise in this site can originate from the.

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Metastasis of breast cancer to major duodenal papilla. Tiago Bastos 1aThiago F. Souza 1aJose P.

Metastasis is an infrequent cause of tumor involvement of the major duodenal papilla and of cholestasis. We report zmpula case of obstructive jaundice due to a metastatic breast carcinoma to the major duodenal papilla, and assess curative and palliative treatment that interventional endoscopy can offer.

Ampulla of Vater; Breast neoplasms; Jaundice source: Ampolla de Vater; Neoplasias de la mama; Ictericia fuente: In this report we present a case of biliary obstruction due to metastatic breast cancer to the major duodenal papilla. The patient underwent a modified mastectomy and adjuvant chemotherapy for bone metastases to the lumbar spine in December In August the patient presented abdominal pain and cholestasis syndrome. The laboratory evaluation revealed bilirubin totals 7.

Associated with such findings, a 15 mm dilatation of the intra and extrahepatic biliary tree was observed by abdominal ultrasound. The patient underwent an endoscopic retrograde cholangiopancreatography ERCPwhere a swollen, friable and bleeding papilla was found, with necrotic areas.

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Dilation of the intra and extrahepatic bile duct 15 mm was noticed. A papillotomy was performed and a 10 French x 9 cm plastic stent was placed in ammpula common bile duct. Histological examination showed a carcinoma, with infiltration in the duodenal mucosa. An endoscopic ultrasound EUS was recommended, and it demonstrated infiltration of the injury until the muscular layer of the duodenal wall, without suspicious regional lymph nodes.

Tumors of ampulla of Vater: A case series and review of chemotherapy options

Due to the invasive nature of the lesion, palliative treatment was offered with replacement of the plastic stent for a metallic one the patient had significant improvement of the cholestatic syndrome and abdominal pain.

Malignant vatdr affecting the major duodenal papilla are rare, and the adenocarcinoma is the histological type in almost all cases, but occasionally other histological types such as carcinoid tumors, squamous cell and mucinous carcinomas can be found 4.

Within this context, the metastases of breast tumor to the major duodenal papilla are a very rare event, with only three cases reported in the world literature, all due to lobular breast carcinoma. Immunohistochemistry plays a key ve for indicating the histological type of the tumor, since the metastases of cajcer breast carcinoma to the gastrointestinal tract have an endoscopic, radiological and histological aspect similar to the adenocarcinoma poorly differentiated with signet ring cells.

Therefore, it is very important to differentiate these kinds of malignancies, since each of them has a different prognosis and treatment 3. Some authors recommend that for lesions less than 10 mm, with no amoula appearance of malignancy,to perform endoscopic resection of the tumor 8,9. In cases of invasive tumors, duodenopancreatectomy is the treatment of choice.

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Although metastases of breast carcinomas are infrequent to the gastrointestinal tract, neoplasms of the juxtapapillary region should be suspected, especially at an early a,pula, since curative resection can be offered.

None of the authors have any conflict of interests to amlula. Infiltrating lobular carcinoma of the breast. Clinicopathologic analysis of cases with reference to data on conservative therapy and metastatic patterns.

Wong K, Henderson IC. Management of metastatic breast cancer. Utility of immunohistochemistry in distinguishing primary adenocarcinomas from metastatic breast carcinomas in the gastrointestinal tract.

Tumors of ampulla of Vater: A case series and review of chemotherapy options

Arch Pathol Lab Med. Yamaguchi K, Enjoji M. Carcinoma of the ampulla of vater. A clinicopathologic study and pathologic staging of cases of carcinoma and 5 cases of adenoma.

Huibregtse KTytgat GN.

Carcinoma of the ampulla of Vater: Polypoid tumors of the major duodenal papilla: Bassan M, Bourke M. Focal early stage cancer in ampullary adenoma: Conclusion Although metastases of breast carcinomas are infrequent to the gastrointestinal tract, neoplasms of the juxtapapillary region should be suspected, especially at an early stage, since curative resection can be offered.