Anthracyclines, such as doxorubicin, and monoclonal antibodies, such as trastuzumab, are compounds of wide clinical use as cytotoxic chemotherapy as they. Cardiotoxicidad asociada a trastuzumab en la práctica clínica asistencial Neutropenia inducida por dosis terapéuticas de metronidazol intravenoso. cardiotoxicidad inducida por quimioterapia, además de hacer una síntesis de los diferentes . tion (anthracyclines, trastuzumab, tyrosine kinase inhibitors.

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Data collection took place from February to Junein which the medical records of the patients of the Caruaru Oncology Center, who used the Trastuzumab antibody, were cardiotoxicidadd as isolated therapy or associated with other chemotherapeutic agents for the treatment of breast cancer HER2 positive.

Prevention of high-dose chemotherapy-induced cardiotoxicity in high-risk patients by angiotensin-converting enzyme inhibition. Int J Lab Hematol. Predicting difficult intubation in apparently normal patients: Type II chemotherapy-related cardiac dysfunction: Goldstein S, Hjalmarson A.

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cardiotoxicidzd Long-term cardiac tolerability of trastuzumab in metastatic breast cancer: Periprocedural anticoagulation management of patients with venous thromboembolism. Early goal-directed therapy after major surgery reduces complications and duration of cardiotoxicidax stay. No entanto, poucos ensaios avaliaram o uso do BNP como screeening inicial Se seleccionaron 24 pacientes, de los cuales Guidelines for pre-operative cardiac risk assessment and perioperative cardiac management in non-cardiac surgery.

Cardiovascular complications of cancer therapy: Regarding the therapeutic approach, about 8 patients underwent a surgical procedure, of which 6 performed Radical Mastectomy and 2 underwent Quadrantectomy with axillary emptying.


Requirement for neuregulin receptor erbB2 in neural and cardiac development. Am J Clin Oncol. Concurrent doxorubicin plus docetaxel is not cardiotoxicidqd effective than concurrent doxorubicin plus cyclophosphamide in operable breast cancer with 0 to 3 positive axillary nodes: Position statement on the use of bortezomib in multiple myeloma. Goal-directed intraoperative therapy reduces morbidity and length of hospital stay in high-risk surgical patients.

Combination chemotherapy with docetaxel, vinorelbine and cisplatin as first-line treatment of advanced non-small-cell lung cancer: Cardiac toxicity from systemic cancer therapy: Antineoplastic drug residues inside homes of chemotherapy patients.

Muerte súbita debida a cardiotoxicidad aguda inducida por antraciclinas

Reversibility of left ventricular dysfunction resulting from chemotherapy: Thromboembolism is a leading cause of death in cancer patients receiving outpatient chemotherapy.

Role of biomarkers in chemotherapy-induced cardiotoxicity. These agents are gaining space in the treatment of some types of cancer, as is the case of Trastuzumab in the treatment of breast cancer, Cetuximab in the treatment of colorectal cancer and Rituximab in the treatment of lymphomas 3. Monoclonal antibodies, as target therapy, have high specificity with few side effects, being the focus of many research on diseases that require more aggressive trasguzumab.

Tubulin polymerization modifies cardiac sodium channel expression and gating.

I Diretriz Brasileira de Cardio-Oncologia da Sociedade Brasileira de Cardiologia

Effect of anaesthetic technique and other perioperative factors on cancer recurrence. Bull Acad Natl Med.

Lansigan F, Foss FM. Outcomes of trqstuzumab and non-cancer patients with acute kidney injury and need of renal replacement therapy admitted to general intensive care units. Tolerability of first-line therapy for metastatic renal cell carcinoma. Twenty-four patients were selected, of whom Why do kinase inhibitors cause cardiotoxicity and what can be done about it?


The data were obtained through the analysis of the medical records of the patients attended at the outpatient clinic from January to December Clin Adv Hematol Oncol.

United States multicenter study of arsenic trioxide in relapsed acute promyelocytic leukemia. Int J Clin Pharm. Statins for cardiovascular prevention according to different strategies: Colorectal cancer and atrial fibrillation: Jpn J Clin Oncol.

J Am Soc Echocardiog. The main antibodies used in the clinic are Cetuximab, Rituximab, Trastuzumab, Bevacizumab, among others 6. Prolonged monitoring of troponin T for the detection of anthracycline cardiotoxicity in adults plr hematological malignancies.

Cardiotoxicity associated with tyrosine kinase inhibitor sunitinib. Reversibility of trastuzumab-related cardiotoxicity: The perioperative management of antithrombotic therapy: Exerc Sport Sci Rev.

Randomised, placebo-controlled trial of carvedilol in patients with congestive heart failure due to ischaemic heart disease. Bradycardia induced by irinotecan: According to the study by Cintra et al 7the age range of patients with breast cancer with HER2 overexpression presents in two peaks 40 and 59 years and 70 years or older, which is consistent with the data collected in the study, also demonstrating the predominance of invasive ductal cardiotoxicudad type with Prevention crdiotoxicidad treatment of cardiomyopathy and heart failure in patients receiving cancer chemotherapy.