ESTUDIO WHI, REVISTA DE MENOPAUSIA, SALUD, REVISTAS MÉDICAS. Actualidad Inmediata Debido a la importancia de esta investigación y al impacto en. WHI. Progestin. Estrogen. Tibolone. Cardiovascular disease. Tromboembolic disease . Boletín de la Asociación Española para el Estudio de la Menopausia, . Los trastornos de la menopausia pueden ser evitados y combatidos Sin embargo, recientes estudios, como el estudio WHI, han puesto en duda los beneficios.
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Second, it must be stressed that the main goal is women’s health and not hormonal therapies.
Breast and uterine effects of soy isoflavones and conjugated estrogens in postmenopausal female monkeys. This was the case with the WHI, a study aimed at the primary prevention of cardiovascular diseases in healthy postmenopausal women.
Estrogen plus progestin and the risk of coronary heart disease. The observed lower event rate in smokers compared with non-smokers in the hormone group is intriguing.
Annals de Medicina, 87pp. Risks and benefits of estrogen plus progestin in healthy postmenopausal women. The WHI is an important study.
Pooling data for estrogen alone and estrogen plus progestin resulted in increased risks for both endpoints. Strengths of WHIMS-Y include balance in baseline risk factors between treatment groups, standardized and masked data collection, and high rates of retention and on-trial adherence and exposure.
Obst Gynecol, 87pp. It seems that this intriguing question was raised by other people, which esstudio to initiation of a long-term follow-up on younger hormone users. The effects of soy protein containing phytoestrogens on menopausal symptoms in postmenopausal women.
The Nurses’ Health Study and studies from Europe, where estradiol is the commonly prescribed form of estrogen, suggest that the estrogen at lower doses may confer similar benefit” [ 15 ] Luckily one has nowadays an ample choice of strategies and drugs hormonal and non-hormonal that enable a conscientious physician to do his best to restore the confidence of those women who have sought his help.
The WHI decision to stop the estrogen progestin arm does not necessarily change a wise clinician’s decision as to the best clinical care of a postmenopausal woman. WHI does not introduce new rules to good clinical practice. Bone Miner Res, 17pp.
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Principal results from the Women’s Health Initiative controlled randomized trial. Climateric, 3pp.
Beneficial effects of soy phytoestrogen intake menopaudia postmenopausal women with type 2 diabetes. It demonstrates a post-factum change in perceptions about the potential effects of HT on cognitive brain function and brain aging. First came the results menopasuia the estrogen plus progestin arm [2,3], which were summarized by the investigators as follows: Dietary phytoestrogens and their effect on bone: Ipriflavone Multicenter European Fracture Study.
Evaluation of soy phytoestrogens for the treatment of hot flashes in breast cancer survivors: Folia Clin Intern, 49pp.
TERAPIA HORMONAL SUSTITUTIVA: ESTUDIO WHI
So the issue of possible effects of HT on cognitive function and brain aging in young postmenopausal women is still open until further, good-quality data are available.
The Millennium Review, Parthenon Preventing a woman from the benefits of a sound postmenopausal hormone therapy because of the fear of rare side effects does not seem to be satisfactory Medicine Women’s Health Initiative Investigators. J Clin Endocrinol Metab, 86pp. Menopause, 6pp. Clinical effects of standardized soy extract in postmenopausal women: Recent diet and breast cancer risk: Thus this fixed excessive dose for older women does not necessarily reflect optimal good clinical practice and is not followed by any responsible gynaecologist.
Are you a health professional able to prescribe or dispense drugs? Phytoestrogens do not influence lipoprotein levels or endothelial function in healthy postmenopausal women. Given these latest additions to our overall knowledge the policy of EMAS wil be to: Effect of soy protein supplementation on serum lipoproteins, blood pressure, and menopausal symptoms in perimenopausal women.
These data were published in a series of papers during — Several years later, data from an extension trial of up to 4 additional years after discontinuation of HT were released : Breast cancer risk following long-term oestrogen and oestrogen-progestin replacement therapy.